![]() ![]() If a nucleic acid sequence appears to encode a protein, it is of interest to translate the sequence and to analyze the properties of the putative translation product. The typical molecular biologist might want to enter sequence data obtained in the laboratory, then determine if it encoded any proteins or contained any special sequence motifs or restriction sites, construct maps that display any or all of the features of interest, and carry out sequence similarity searches against known sequences. MacVector is a "full-service" sequence analysis application that enables molecular biologists to analyze DNA and protein sequences on their Macintosh or PowerPC computers. The choices are varied, and the programs available range from those with a single function, such as the design of primers for polymerase chain reaction (PCR), to multipurpose products. Like the sequencing techniques themselves, the software available to carry out sequence analysis has become increasingly powerful and swift. Nowadays the main task is not sequence determination it is sequence analysis, with the help of desktop programs. ![]() The sequences that now fill databases have been determined not only by the research groups involved in the major genome sequencing projects, but also piecemeal by individual researchers investigating their genes of interest. Improvements in sequencing methods since that time have led to the rapid sequencing of many millions of base pairs from the genomes of a variety of organisms. MacVector 6.5 Oxford Molecular Group $2950 $395/$795 (upgrade) When nucleic acid sequencing was in its infancy, the mere determination of the sequence of a stretch of DNA was news.
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